Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 11/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640110 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL24170261 | 0.83 | NOS3 (0.41) | KDM4EALDH1A1HPGDSCN1ASCN4A | |
| SCHEMBL15264451 | 0.80 | NOS3 (0.39) | KDM4EALDH1A1KCNH2GAAMAPT | |
| SCHEMBL9504216 | 0.80 | PIK3CD (0.43) | ALDH1A1MAPTCASP1MEN1KMT2A | |
| SCHEMBL9501566 | 0.79 | RAF1 (0.40) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL29631754 | 0.77 | NOS3 (0.40) | KDM4EKCNH2GAAMAPTKMT2A | |
| SCHEMBL11969208 | 0.77 | NOS3 (0.40) | KDM4EKCNH2GAAMAPTKMT2A | |
| SCHEMBL19138468 | 0.76 | ALPL (0.49) | KDM4ESCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL14480886 | 0.74 | KCNH2 (0.69) | SCN1ASCN4AKCNH2SCN5ASCN9A | |
| SCHEMBL8641707 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355598-B1 | BETA-PHENOXYETHYL AMINES AND THEIR USE IN THE PREPARATION OF DYES | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5126481-A | Cyclization, reduction, decyclization | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-5041629-A | Beta-phenoxyethylamines and their use for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0355598-A2 | Beta-phenoxyethyl amines and their use in the preparation of dyes | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |