SCHEMBL9501625

SCHEMBL9501625

CC(C)(C)C1CCC(C2=CC(=O)NC2=O)CC1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.31
OPRK1 P41145 2/20 0.31
OPRL1 P41146 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
GLA P06280 1/20 0.30
ATM Q13315 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8563214 0.85 MAOA (0.34)
SCHEMBL548282 0.85 MAOA (0.34)
SCHEMBL9359727 0.80 ESR2 (0.33)
SCHEMBL5202489 0.77 MAOA (0.41)
SCHEMBL27630042 0.77 MAOA (0.45)
SCHEMBL21496202 0.77 ESR2 (0.34)
SCHEMBL8885354 0.76 MAOA (0.44) GAAMAPT
SCHEMBL28720 0.76 MAOA (0.44) GAAMAPT
SCHEMBL9250741 0.76 MAOA (0.44) GAAMAPT
SCHEMBL28123322 0.76 MAOA (0.44) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372213-B1 PROTECTIVE METHYCRYLATE LAYER FOR POLYCARBONATE, CONTAINING A UV ABSORBER RÖHM GMBH (DE) 1993-05-19 EP disclosed
EP-0283975-B1 COMPATIBLE BLENDS OF POLYCARBONATE AND METHYL METHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1993-04-21 EP disclosed
EP-0372213-A1 Protective methycrylate layer for polycarbonate, containing a UV absorber RÖHM GMBH (DE) 1990-06-13 EP disclosed