Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328415 | 0.85 | MTNR1A (0.65) | MTNR1AMTNR1BEPHX2LPAR1 | |
| SCHEMBL9500010 | 0.82 | TP53 (0.52) | NMBREPHX2KMT2ALMNALPAR1 | |
| SCHEMBL9875138 | 0.80 | KMT2A (0.53) | NMBREPHX2KDM4EKMT2ALMNA | |
| SCHEMBL9501268 | 0.80 | TP53 (0.65) | EPHX2LMNA | |
| SCHEMBL9265604 | 0.76 | EPHX2 (0.58) | EPHX2KMT2ALMNALPAR1 | |
| SCHEMBL26763719 | 0.76 | MTNR1A (0.69) | MTNR1AMTNR1BTAOK1 | |
| SCHEMBL9272350 | 0.75 | EPHX2 (0.58) | EPHX2KMT2ALMNALPAR1MEN1 | |
| SCHEMBL9273423 | 0.75 | EPHX2 (0.61) | EPHX2KMT2ALMNAMEN1 | |
| SCHEMBL9274396 | 0.75 | EPHX2 (0.55) | EPHX2KMT2ALMNAMEN1 | |
| SCHEMBL9265827 | 0.75 | TRPV1 (0.53) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| US-4868210-A | PHENYL UREAS AND PHENYL THIOUREAS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | claimed |
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5030653-A | N-2,6-dialkyl- or n-2,6-dialkoxyphenyl-n-arylalkylurea compounds | WARNER-LAMBERT COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| US-4948806-A | N-2,6-DIALKYL-OR N-2,6-DIALKOXYPHENYL-N'-ARYLALKYLUREA | WARNER-LAMBERT COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| US-4868210-A | PHENYL UREAS AND PHENYL THIOUREAS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |