Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NMBR | P28336 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501682 | 0.80 | NMBR (0.58) | KMT2AMEN1NMBRKDM4ELMNA | |
| SCHEMBL9503218 | 0.80 | MTNR1A (0.48) | KMT2AMEN1NMBRSMN1; SMN2LMNA | |
| SCHEMBL8800082 | 0.79 | KMT2A (0.55) | KMT2AMEN1ALDH1A1PLA2G1BATG4B | |
| SCHEMBL24105930 | 0.76 | PDPK1 (0.56) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL19114860 | 0.76 | PDPK1 (0.56) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL14521490 | 0.76 | PDPK1 (0.56) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9499523 | 0.75 | NMBR (0.48) | KMT2AMEN1NMBRALDH1A1PLA2G1B | |
| SCHEMBL30083855 | 0.75 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL9265604 | 0.73 | EPHX2 (0.58) | KMT2AALDH1A1TRPV1LMNAEPHX2 | |
| SCHEMBL2466144 | 0.73 | PDPK1 (0.61) | KMT2AMEN1ALDH1A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | disclosed |