Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501799 | 0.77 | KDM4E (0.43) | PLA2G7NPC1RAB9ASMN1; SMN2KDM6B | |
| SCHEMBL19410840 | 0.71 | NPC1 (0.38) | NPC1SMN1; SMN2 | |
| SCHEMBL15795680 | 0.70 | GPR84 (0.41) | PLA2G7GPR84 | |
| SCHEMBL9502638 | 0.70 | KDM4E (0.44) | DAGLAHCAR2 | |
| SCHEMBL15795172 | 0.70 | PLA2G4B (0.51) | PLA2G7GPR84 | |
| SCHEMBL15794852 | 0.69 | PLA2G7 (0.41) | PLA2G7SMN1; SMN2GPR84 | |
| SCHEMBL15795489 | 0.69 | GPR84 (0.40) | PLA2G7GPR84 | |
| SCHEMBL1981184 | 0.69 | GPR84 (0.40) | PLA2G7GPR84 | |
| SCHEMBL15795289 | 0.69 | GPR84 (0.40) | PLA2G7GPR84 | |
| SCHEMBL2082262 | 0.68 | HPGD (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |