Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501780 | 0.77 | PLA2G7 (0.44) | NPC1RAB9ASMN1; SMN2GPR84PLA2G7 | |
| SCHEMBL3600150 | 0.74 | CYP11B1 (0.46) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5102757 | 0.67 | ALDH1A1 (0.50) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31299270 | 0.67 | ALDH1A1 (0.53) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24023978 | 0.67 | MAPT (0.50) | — | |
| SCHEMBL8332511 | 0.66 | HPGD (0.53) | HPGD | |
| SCHEMBL6238584 | 0.66 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL10696175 | 0.66 | KDM4E (0.49) | KDM4ENPC1RAB9ASMN1; SMN2DAGLA | |
| SCHEMBL26705850 | 0.66 | ALDH1A1 (0.59) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3598246 | 0.66 | HCAR2 (0.45) | KDM4EDAGLAPLA2G4BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |