Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177974 | 0.84 | ALDH1A1 (0.63) | ALDH1A1MCL1KMT2AKDM4ERXRA | |
| SCHEMBL9501872 | 0.84 | KDM4E (0.55) | ALDH1A1LDHAKDM4EHPGDHSD17B10 | |
| SCHEMBL539134 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL29875598 | 0.78 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL4081642 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MCL1KMT2AKDM4ERXRA | |
| SCHEMBL9179944 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL11556630 | 0.78 | LDHA (0.54) | ALDH1A1LDHAMCL1KMT2AKDM4E | |
| SCHEMBL28054675 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MCL1KMT2ABCL2L1KDM4E | |
| SCHEMBL17908039 | 0.75 | ALDH1A1 (0.73) | ALDH1A1MCL1KMT2AKDM4ERXRA | |
| SCHEMBL9856341 | 0.75 | LDHA (0.59) | ALDH1A1LDHAMCL1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |