SCHEMBL9501926

SCHEMBL9501926

BrC#COc1ccccc1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.37
KDM4E B2RXH2 3/20 0.34
RAB9A P51151 5/20 0.33
NPC1 O15118 4/20 0.33
LMNA P02545 4/20 0.33
GRM4 Q14833 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
LY96 Q9Y6Y9 1/20 0.32
CYP1A2 P05177 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8523291 0.83
SCHEMBL30692445 0.80 HTR7 (0.40) HTR7RAB9ANPC1LMNAGRM4
SCHEMBL7558433 0.74 HTR7 (0.38) HTR7KDM4ERAB9ANPC1LMNA
SCHEMBL8848905 0.74 LMNA (0.40) HTR7KDM4ERAB9ANPC1LMNA
SCHEMBL1191549 0.74 HTR7 (0.38) HTR7KDM4ERAB9ANPC1LMNA
SCHEMBL30692450 0.72 LMNA (0.39) HTR7KDM4ERAB9ANPC1LMNA
SCHEMBL727333 0.69 ALDH1A1 (0.48) HTR7RAB9ANPC1LMNAGRM4
SCHEMBL22131083 0.69 HTR7 (0.45) HTR7KDM4ERAB9ANPC1LMNA
SCHEMBL3842507 0.67 MAPK1 (0.46) HTR7RAB9ANPC1LMNAGRM4
SCHEMBL10934919 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249375-B1 A PROCESS OF DYEING AND FLAME RETARDING AN ARAMID FIBRE OR FABRIC Burlington Industries, Inc. (US) 1993-05-26 EP claimed