SCHEMBL9501976

SCHEMBL9501976

COC(=O)c1ccc(NC(=O)C(=O)NN)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
MAPT P10636 6/20 0.59
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 2/20 0.59
GAA P10253 2/20 0.59
PTPN11 Q06124 1/20 0.58
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HTT P42858 1/20 0.56
LMNA P02545 1/20 0.54
ATM Q13315 1/20 0.54
POLB P06746 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PKM P14618 1/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17203068 0.84 MAPT (0.69) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL4957765 0.81 MAPT (0.72) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL2833648 0.80 ALDH1A1 (0.66) MEN1KMT2AMAPTALDH1A1NPC1
SCHEMBL9501086 0.80 KDM4E (0.65) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL1588322 0.80 LMNA (0.56) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL20764440 0.79 MEN1 (0.67) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL182181 0.79 MAPT (0.64) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL529066 0.79 MEN1 (0.61) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL8660366 0.77 NPC1 (0.83) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL9551946 0.77 MAPT (0.70) KDM4EMEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed