Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502352 | 0.89 | ACAT1 (0.77) | ACAT1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9502933 | 0.87 | ACAT1 (0.82) | ACAT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9503027 | 0.85 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9502100 | 0.85 | ACAT1 (0.72) | ACAT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9502212 | 0.85 | ACAT1 (0.72) | ACAT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9502255 | 0.85 | ACAT1 (0.72) | ACAT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9503247 | 0.81 | ACAT1 (0.76) | ACAT1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9502459 | 0.81 | ACAT1 (0.72) | ACAT1KMT2AMAPTKDM4ETP53 | |
| SCHEMBL9502479 | 0.80 | ACAT1 (0.80) | ACAT1TP53TSHRPLK1 | |
| SCHEMBL9505689 | 0.79 | ACAT1 (0.68) | ACAT1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543891-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |