Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501084 | 0.75 | MEN1 (0.42) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL9503269 | 0.75 | NPBWR1 (0.35) | LMNANPSR1ALDH1A1 | |
| SCHEMBL11774292 | 0.70 | KMT2A (0.42) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL7922604 | 0.68 | GAA (0.40) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL9501160 | 0.68 | LMNA (0.36) | MEN1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL9504429 | 0.68 | MEN1 (0.38) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL7910217 | 0.68 | GAA (0.43) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL9501824 | 0.67 | LMNA (0.31) | LMNANPSR1 | |
| SCHEMBL7917515 | 0.67 | GAA (0.39) | MEN1KMT2AGAALMNACYP3A4 | |
| SCHEMBL11770905 | 0.66 | NPSR1 (0.51) | MEN1KMT2AGAALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5188832-A | Triazine-dione compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0383285-A2 | Agent against fish and insect parasites | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-22 | — | — | EP | disclosed |