Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504429 | 0.90 | MEN1 (0.38) | LMNAMEN1GAAKMT2AMAPK1 | |
| SCHEMBL9501084 | 0.90 | MEN1 (0.42) | LMNAMEN1GAAKMT2AMAPK1 | |
| SCHEMBL9502415 | 0.85 | KMT2A (0.34) | LMNAMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL10502467 | 0.83 | NPC1 (0.40) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9504425 | 0.82 | NPBWR1 (0.35) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9500884 | 0.77 | MEN1 (0.37) | LMNAMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL10733171 | 0.76 | HTR1A (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9500876 | 0.73 | THRB (0.38) | NPC1RAB9A | |
| SCHEMBL7919150 | 0.71 | TSHR (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7922604 | 0.70 | GAA (0.40) | LMNAMEN1GAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5188832-A | Triazine-dione compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0383285-A2 | Agent against fish and insect parasites | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-22 | — | — | EP | disclosed |
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4640917-A | 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-03 | — | — | US | disclosed |
| EP-0154885-A1 | Substituted 2-phenyl-hexahydro-1,2,4-triazine-2,5-diones, method for their preparation, their use as veterinary medicines and for combating protozoes | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-18 | — | — | EP | disclosed |