Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501160 | 0.90 | LMNA (0.36) | MEN1KMT2AGAALMNAMAPK1 | |
| SCHEMBL9501084 | 0.90 | MEN1 (0.42) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL9502415 | 0.88 | KMT2A (0.34) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL9500884 | 0.87 | MEN1 (0.37) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL10733171 | 0.85 | HTR1A (0.36) | MEN1KMT2AMAPTL3MBTL1CYP3A4 | |
| SCHEMBL10501494 | 0.73 | KMT2A (0.36) | MEN1KMT2AGAAMAPTCYP3A4 | |
| SCHEMBL9504425 | 0.72 | NPBWR1 (0.35) | LMNAMAPK1 | |
| SCHEMBL10502467 | 0.72 | NPC1 (0.40) | LMNAMAPTMAPK1 | |
| SCHEMBL7919150 | 0.71 | TSHR (0.38) | MEN1KMT2AMAPT | |
| SCHEMBL7922604 | 0.70 | GAA (0.40) | MEN1KMT2AGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154885-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-2,5-DIONES, METHOD FOR THEIR PREPARATION, THEIR USE AS VETERINARY MEDICINES AND FOR COMBATING PROTOZOES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | claimed |
| US-5188832-A | Triazine-dione compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| US-4640917-A | 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-03 | — | — | US | disclosed |