Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512589 | 0.81 | LMNA (0.64) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL715377 | 0.80 | KDM4E (0.59) | KDM4EKMT2AGFERRXFP1MAPT | |
| Ethane SCHEMBL27571371 | 0.79 | ALDH1A1 (0.59) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL344115 | 0.79 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL342600 | 0.79 | ALDH1A1 (0.62) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL9499856 | 0.78 | KDM4E (0.52) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL22882832 | 0.78 | EGFR (0.50) | KDM4EMAPTMCL1ALDH1A1HPGD | |
| SCHEMBL10915110 | 0.77 | HSD17B10 (0.47) | KDM4EKMT2AMAPTMEN1POLB | |
| SCHEMBL4844487 | 0.77 | KMT2A (0.50) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL9501001 | 0.75 | KDM4E (0.49) | KDM4EKMT2AGFERRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |