Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499751 | 0.83 | LMNA (0.56) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8335461 | 0.81 | MEN1 (0.54) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL20714769 | 0.81 | MAPT (0.50) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL12289538 | 0.80 | MAPT (0.66) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26598921 | 0.80 | LMNA (0.52) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL9776299 | 0.79 | HCAR3 (0.64) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11875109 | 0.78 | MEN1 (0.51) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL30007928 | 0.77 | VCAM1 (0.69) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL22382437 | 0.77 | ALDH1A1 (0.70) | LMNAVCAM1ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11879055 | 0.77 | MEN1 (0.50) | LMNAVCAM1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414585-B1 | KERATINOUS FIBRES DYE COMPOSITION CONTAINING AN INDOLE DYE AND AT LEAST A PARAPHENYLENEDIAMINE HAVING A SECONDARY AMINO GROUP AND PROCESS | L'OREAL (FR) | 1993-04-21 | — | — | EP | disclosed |
| EP-0414585-A1 | Keratinous fibres dye composition containing an indole dye and at least a paraphenylenediamine having a secondary amino group and process | L'OREAL (FR) | 1991-02-27 | — | — | EP | disclosed |