Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505608 | 0.85 | PTGS2 (0.55) | PTGS2CETPALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9502657 | 0.77 | CYP19A1 (0.47) | PTGS2CA2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11360737 | 0.74 | CETP (0.54) | CETPALDH1A1SMN1; SMN2NPSR1HTT | |
| SCHEMBL30548748 | 0.72 | MAOA (0.44) | CA2CETPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12768022 | 0.72 | PSIP1 (0.73) | PSIP1PTGS2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20495594 | 0.72 | MAOA (0.44) | CA2CETPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11367064 | 0.72 | CETP (0.51) | CETPALDH1A1SMN1; SMN2NPSR1HTT | |
| SCHEMBL11353345 | 0.72 | CETP (0.55) | CETPALDH1A1SMN1; SMN2NPSR1HTT | |
| SCHEMBL11359720 | 0.71 | CETP (0.54) | CETPSMN1; SMN2NPSR1HTTLMNA | |
| SCHEMBL5143535 | 0.69 | PSIP1 (0.63) | PSIP1PTGS2SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |