Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL2016852 | 0.86 | CYP1A2 (0.63) | MTNR1ACYP1A2CYP2A6 | |
| SCHEMBL30277953 | 0.85 | CYP1A2 (0.55) | MTNR1ACYP1A2CYP2A6MTNR1B | |
| SCHEMBL774076 | 0.85 | CYP1A2 (0.55) | MTNR1ACYP1A2CYP2A6MTNR1B | |
| SCHEMBL28776166 | 0.84 | CYP1A2 (0.52) | MTNR1ACYP1A2CYP2A6HTR2AMTNR1B | |
| 1-Naphthol SCHEMBL7584597 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2A6NQO2 | |
| SCHEMBL9502674 | 0.80 | CTDSP1 (0.49) | MTNR1ACYP1A2CTDSP1MTNR1BNQO2 | |
| SCHEMBL7079680 | 0.80 | MTNR1A (0.48) | MTNR1ACTDSP1MTNR1BHTR2CHTR2B | |
| SCHEMBL28628067 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP2A6 | |
| SCHEMBL18674135 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP2A6CTDSP1 | |
| 1-Naphthol SCHEMBL28030286 | 0.79 | HDAC4 (0.61) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135848-A | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| CN-115536502-A | Preparation method and application of 7-methoxy-1-naphthol | 阜阳欣奕华制药科技有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-113549002-A | D-sigma-A configuration compound, and synthesis method and application thereof | 西安近代化学研究所 | 2021-10-26 | — | — | CN | claimed |
| US-8212077-B2 | Process for the synthesis of agomelatine | LES LABORATOIRES SERVIER (FR) | 2012-07-03 | — | — | US | claimed |
| EP-2151428-B1 | Process for the preparation of agomelatin | SERVIER LAB (FR) | 2012-03-07 | — | — | EP | claimed |
| WO-2010015745-A1 | NOVEL METHOD FOR THE SYNTHESIS OF AGOMELATINE | LES LABORATOIRES SERVIER (FR) | 2010-02-11 | — | — | WO | claimed |
| US-20100036162-A1 | Process for the synthesis of agomelatine | LES LABORATOIRES SERVIER (FR) | 2010-02-11 | — | — | US | claimed |
| EP-2151428-A1 | Process for the preparation of agomelatin | Les Laboratoires Servier (FR) | 2010-02-10 | — | — | EP | claimed |
| EP-0697854-B1 | USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS | HENKEL KGAA (DE) | 1997-03-05 | — | — | EP | claimed |
| EP-0697854-A1 | USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS | HENKEL KGAA (DE) | 1996-02-28 | — | — | EP | claimed |
| WO-1994026241-A1 | USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-11-24 | — | — | WO | claimed |
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2024-12-10 | — | — | US | disclosed |
| CN-117865925-A | 3, 4-benzocoumarin compound based on complex functional aromatic hydrocarbon and preparation method and application thereof | 上海瑞苷生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116135848-B | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-03-12 | — | — | CN | disclosed |
| EP-4153555-B1 | PHOTOOXIDATION OF PHENOLIC COMPOUNDS | DSM IP ASSETS BV (NL) | 2024-01-31 | — | — | EP | disclosed |
| US-3956294-A | AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3954782-A | 2,6-Hydrazino-3-pyridine carboxyamides | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3947463-A | Certain 2-amino-nicotinonitrile derivatives | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-30 | — | — | US | disclosed |
| US-3946024-A | INTERMEDIATES FOR AZO DYES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3935267-A | CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | MTNR1A 190/4885CYP1A2 718/4885CYP2A6 2081/4885 |
| US-20100036162-A1 | Process for the synthesis of agomelatine | COMT, PNMT, TPH1 | MTNR1A 331/4885CYP1A2 45/4885CYP2A6 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.