Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502183 | 0.89 | TP53 (0.47) | KDM4ECD274BCHECHRM2CHRM4 | |
| SCHEMBL9504108 | 0.86 | TP53 (0.44) | KDM4ECD274BCHECHRM2CHRM4 | |
| SCHEMBL9501482 | 0.84 | POLB (0.39) | SLC2A1KDM4EBCHECHRM2CHRM4 | |
| SCHEMBL9501109 | 0.84 | TSHR (0.45) | KDM4EHTTCD274BCHECHRM2 | |
| SCHEMBL9502824 | 0.84 | BCHE (0.41) | ALOX15CD274BCHECHRM2CHRM4 | |
| SCHEMBL10518196 | 0.80 | BCHE (0.38) | ALOX15CD274BCHECHRM2CHRM4 | |
| SCHEMBL9501464 | 0.78 | BCHE (0.38) | KDM4ECD274BCHEACHEMEN1 | |
| SCHEMBL27728143 | 0.65 | ALDH1A1 (0.53) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21730497 | 0.64 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2CYP2D6MEN1KMT2A | |
| SCHEMBL9504044 | 0.64 | POLB (0.38) | KDM4EHTTSMN1; SMN2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |