Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518196 | 0.96 | BCHE (0.38) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9502756 | 0.84 | SLC2A1 (0.40) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9502183 | 0.81 | TP53 (0.47) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9504108 | 0.78 | TP53 (0.44) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10516294 | 0.77 | HTR6 (0.38) | CYP2D6HTR6HIF1ACYP3A4 | |
| SCHEMBL9501482 | 0.77 | POLB (0.39) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9501109 | 0.77 | TSHR (0.45) | BCHECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9501464 | 0.76 | BCHE (0.38) | BCHEACHEALDH1A1L3MBTL1CD274 | |
| SCHEMBL10516301 | 0.69 | HTR6 (0.38) | CYP2D6HTR6HIF1ACYP3A4 | |
| SCHEMBL10516286 | 0.69 | HTR6 (0.45) | CYP2D6HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |