Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518194 | 0.96 | LMNA (0.46) | LMNASLC6A2SLC6A4KDM4EKMT2A | |
| SCHEMBL9502751 | 0.83 | KDM4E (0.39) | LMNAKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9502176 | 0.80 | KDM4E (0.48) | LMNAKDM4EKMT2APOLBALDH1A1 | |
| SCHEMBL9504097 | 0.77 | KDM4E (0.45) | LMNAKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL9502833 | 0.76 | SLC6A4 (0.44) | LMNASLC6A2SLC6A4KDM4EKMT2A | |
| SCHEMBL9501107 | 0.75 | TSHR (0.48) | LMNAKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL593284 | 0.70 | LMNA (0.96) | LMNASLC6A2SLC6A4KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL2924720 | 0.68 | LMNA (1.00) | LMNASLC6A2SLC6A4KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7417639 | 0.68 | LMNA (1.00) | LMNASLC6A2SLC6A4KDM4EKMT2A | |
| SCHEMBL13995920 | 0.66 | KDM4E (0.46) | LMNAKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |