Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504097 | 0.96 | KDM4E (0.45) | KDM4ETDP1CYP2D6PKMTP53 | |
| SCHEMBL9502751 | 0.89 | KDM4E (0.39) | KDM4ETDP1CYP2D6KMT2AALDH1A1 | |
| SCHEMBL9501107 | 0.88 | TSHR (0.48) | KDM4ETDP1KMT2AALDH1A1LMNA | |
| SCHEMBL9502822 | 0.80 | LMNA (0.50) | KDM4EKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL9502192 | 0.80 | TDP1 (0.43) | KDM4ETDP1CYP2D6PKMTP53 | |
| SCHEMBL10518194 | 0.77 | LMNA (0.46) | KDM4ETDP1KMT2AALDH1A1LMNA | |
| SCHEMBL9501073 | 0.77 | GAA (0.59) | CYP2D6PKMKMT2AALDH1A1LMNA | |
| SCHEMBL12726868 | 0.73 | CYP2D6 (0.76) | CYP2D6PKMTP53KMT2AALDH1A1 | |
| SCHEMBL9502196 | 0.71 | CYP2D6 (0.47) | KDM4ECYP2D6PKMKMT2AALDH1A1 | |
| SCHEMBL10386225 | 0.69 | ALDH1A1 (0.45) | KDM4ECYP2D6PKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | claimed |