Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 11/20 | 0.73 |
| ▸ | HEXB | P07686 | 11/20 | 0.73 |
| ▸ | OGA | O60502 | 1/20 | 0.73 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | AHR | P35869 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | STAT6 | P42226 | 1/20 | 0.65 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.65 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396164 | 0.96 | SIRT1 (0.75) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL9504104 | 0.95 | SIRT1 (0.69) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL10568369 | 0.92 | SIRT1 (0.69) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL9500513 | 0.91 | SIRT1 (0.71) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL9500472 | 0.91 | SIRT1 (0.67) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL14539494 | 0.89 | FTO (0.69) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL9092319 | 0.87 | SIRT1 (0.63) | HEXAHEXBOGAFTOCYP2D6 | |
| Elinafide SCHEMBL16213332 | 0.87 | FTO (0.79) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL9091823 | 0.86 | SIRT1 (0.65) | HEXAHEXBOGAFTOCYP2D6 | |
| SCHEMBL2365312 | 0.86 | HEXA (0.74) | HEXAHEXBOGAFTOCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281902-B1 | BIS-NAPHTHALIMIDES, THEIR PREPARATION AND USE | KNOLL AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4874863-A | Bisnaphthalimides | KNOLL AG (DE) | 1989-10-17 | — | — | US | disclosed |