Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.75 |
| ▸ | HEXA | P06865 | 11/20 | 0.68 |
| ▸ | HEXB | P07686 | 11/20 | 0.68 |
| ▸ | OGA | O60502 | 1/20 | 0.68 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.61 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504104 | 0.96 | SIRT1 (0.69) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL9502888 | 0.96 | HEXA (0.73) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL10568369 | 0.94 | SIRT1 (0.69) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL9500472 | 0.92 | SIRT1 (0.67) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL9500513 | 0.92 | SIRT1 (0.71) | SIRT1HEXAHEXBOGAFTO | |
| Elinafide SCHEMBL16213332 | 0.90 | FTO (0.79) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL9092319 | 0.89 | SIRT1 (0.63) | SIRT1HEXAHEXBOGAFTO | |
| SCHEMBL9091823 | 0.88 | SIRT1 (0.65) | SIRT1HEXAHEXBOGAFTO | |
| Elinafide SCHEMBL6256967 | 0.86 | SIRT1 (1.00) | SIRT1HEXAHEXBOGAMEN1 | |
| Elinafide SCHEMBL29441732 | 0.86 | SIRT1 (1.00) | SIRT1HEXAHEXBOGAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175292-A1 | Antioxidants Having Aromatic Structures Reacting with Superoxide | TOUR JAMES (US) | 2016-06-23 | — | — | US | disclosed |
| US-5981753-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| EP-0714387-B1 | NEW BIS-NAPHTHALIMIDES FOR THE TREATMENT OF CANCER | BASF AG (DE) | 1998-05-27 | — | — | EP | disclosed |
| US-5616589-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175292-A1 | Antioxidants Having Aromatic Structures Reacting with Superoxide | GPX4, TXN2, MPO | SIRT1 851/4885HEXA 2410/4885HEXB 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.