Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543293 | 0.74 | FTO (1.00) | FTOALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29938908 | 0.74 | FTO (1.00) | FTOALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL15799957 | 0.73 | FTO (0.52) | FTOMAOAALDH1A1MEN1NPC1 | |
| SCHEMBL1566252 | 0.71 | MAOA (0.65) | FTOMAOAALDH1A1MEN1NPC1 | |
| SCHEMBL10013901 | 0.70 | FTO (0.74) | FTOMAOAALDH1A1MEN1NPC1 | |
| SCHEMBL2195036 | 0.70 | ALDH1A1 (0.72) | MAOAALDH1A1MEN1NPC1MAPT | |
| SCHEMBL13165575 | 0.69 | ALDH1A1 (0.67) | MAOAALDH1A1MEN1NPC1MAPT | |
| SCHEMBL22321720 | 0.69 | MAOA (0.83) | MAOAALDH1A1MEN1NPC1MAPT | |
| SCHEMBL4291944 | 0.69 | MAOA (0.89) | MAOAALDH1A1MEN1NPC1MAPT | |
| SCHEMBL5838218 | 0.68 | ALDH1A1 (0.69) | MAOAALDH1A1MEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |