Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159294 | 0.73 | HTR2B (0.37) | MAPK1CYP3A4ADRA2BADRA2AALDH1A1 | |
| SCHEMBL9503524 | 0.72 | ALDH1A1 (0.34) | ALDH1A1 | |
| Water SCHEMBL1567615 | 0.69 | MTNR1B (0.40) | GABRA1GABRB2AKR1B1MAPTCYP1A2 | |
| SCHEMBL5824091 | 0.67 | GABRA1 (0.58) | GABRA1GABRB2AKR1B1MAPTMEN1 | |
| SCHEMBL9455879 | 0.67 | GABRA1 (0.49) | GABRA1GABRB2AKR1B1MAPTMAPK1 | |
| SCHEMBL10389620 | 0.67 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1MAPTMEN1 | |
| SCHEMBL17498090 | 0.67 | GABRA1 (0.41) | GABRA1GABRB2ADRA2BADRA2CADRA2A | |
| SCHEMBL29763626 | 0.66 | GABRA1 (0.56) | GABRA1GABRB2AKR1B1MAPTMEN1 | |
| SCHEMBL173300 | 0.66 | GABRA1 (0.56) | GABRA1GABRB2AKR1B1MAPTMEN1 | |
| SCHEMBL9092024 | 0.66 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357742-B1 | NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES | ROUSSEL-UCLAF (FR) | 1993-06-09 | — | — | EP | claimed |
| EP-0357742-A1 | NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES. | ROUSSEL UCLAF (FR) | 1990-03-14 | — | — | EP | disclosed |
| EP-0356454-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN. | UPJOHN CO (US) | 1990-03-07 | — | — | EP | disclosed |
| WO-1989008096-A1 | NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES | ROUSSEL-UCLAF (FR) | 1989-09-08 | — | — | WO | disclosed |
| WO-1988008002-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1988-10-20 | — | — | WO | disclosed |