Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361163 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL9506092 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL23768982 | 0.80 | HPGD (0.63) | ALDH1A1LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL9361525 | 0.79 | LMNA (0.57) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL3603021 | 0.79 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL17761132 | 0.78 | LMNA (0.56) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL15999477 | 0.78 | ALDH1A1 (0.72) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL16324795 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL21081374 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBMAPTPRMT5 | |
| SCHEMBL9503748 | 0.75 | MAPT (0.56) | ALDH1A1LMNAPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |