Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675578 | 0.88 | SMN1; SMN2 (0.56) | ALDH1A1HPGDKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL9675538 | 0.85 | NAMPT (0.45) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL9503149 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL11571129 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HPGDKMT2ASMN1; SMN2POLB | |
| SCHEMBL9361444 | 0.79 | HPGD (0.56) | ALDH1A1HPGDPTGER4KMT2AHSD17B10 | |
| SCHEMBL14094315 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HPGDPTGER4SMN1; SMN2POLB | |
| SCHEMBL9502331 | 0.77 | ACAT1 (0.54) | ALDH1A1HPGDSMN1; SMN2GAARAB9A | |
| SCHEMBL9502125 | 0.77 | ACAT1 (0.54) | ALDH1A1HPGDSMN1; SMN2GAARAB9A | |
| SCHEMBL1468005 | 0.77 | PTGER4 (0.69) | ALDH1A1HPGDPTGER4HSD17B10SMN1; SMN2 | |
| SCHEMBL9362329 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1HPGDKMT2AHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |