Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503117 | 0.94 | ACAT1 (0.38) | L3MBTL1HPGDSMN1; SMN2MAPTACAT1 | |
| SCHEMBL9692984 | 0.94 | ACAT1 (0.38) | L3MBTL1HPGDSMN1; SMN2MAPTACAT1 | |
| SCHEMBL9505639 | 0.93 | HPGD (0.34) | KMT2AL3MBTL1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL9503970 | 0.85 | MAPT (0.35) | MAPTACAT1ALDH1A1 | |
| SCHEMBL9502277 | 0.83 | MAPT (0.35) | HTTMAPTALDH1A1 | |
| SCHEMBL9692603 | 0.83 | ACAT1 (0.36) | L3MBTL1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL9502309 | 0.82 | ACAT1 (0.37) | L3MBTL1HPGDSMN1; SMN2HTTMAPT | |
| SCHEMBL9506112 | 0.81 | ACAT1 (0.39) | L3MBTL1HPGDSMN1; SMN2RAB9AHTT | |
| SCHEMBL9677499 | 0.80 | HPGD (0.36) | KMT2AL3MBTL1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL9503199 | 0.77 | HPGD (0.47) | KMT2AL3MBTL1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |