Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503117 | 0.95 | ACAT1 (0.38) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9692984 | 0.95 | ACAT1 (0.38) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9503202 | 0.93 | KMT2A (0.36) | HPGDMAPTACAT1SMN1; SMN2HTT | |
| SCHEMBL9502277 | 0.84 | MAPT (0.35) | MAPTGAANAMPTPOLBHTT | |
| SCHEMBL9692603 | 0.84 | ACAT1 (0.36) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9503970 | 0.83 | MAPT (0.35) | MAPTACAT1NAMPTPOLBHDAC8 | |
| SCHEMBL9502309 | 0.83 | ACAT1 (0.37) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9506112 | 0.82 | ACAT1 (0.39) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9505636 | 0.77 | ACAT1 (0.45) | HPGDMAPTGAAACAT1SMN1; SMN2 | |
| SCHEMBL9692436 | 0.76 | SMN1; SMN2 (0.39) | HPGDMAPTGAASMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |