Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502309 | 0.99 | ACAT1 (0.37) | ACAT1LMNAHTTRECQLPOLB | |
| SCHEMBL9692984 | 0.89 | ACAT1 (0.38) | ACAT1LMNAPOLBMGLLL3MBTL1 | |
| SCHEMBL9503117 | 0.89 | ACAT1 (0.38) | ACAT1LMNAPOLBMGLLL3MBTL1 | |
| SCHEMBL9505690 | 0.86 | L3MBTL1 (0.41) | ACAT1LMNAHTTPOLBL3MBTL1 | |
| SCHEMBL9505639 | 0.84 | HPGD (0.34) | ACAT1LMNAHTTPOLBL3MBTL1 | |
| SCHEMBL9503202 | 0.83 | KMT2A (0.36) | ACAT1HTTL3MBTL1HPGDMAPT | |
| SCHEMBL9506112 | 0.78 | ACAT1 (0.39) | ACAT1HTTL3MBTL1HPGDMAPT | |
| SCHEMBL9692556 | 0.78 | HDAC3 (0.43) | LMNAHTTRECQLPOLBL3MBTL1 | |
| SCHEMBL9503973 | 0.77 | ACAT1 (0.60) | ACAT1LMNAPOLBL3MBTL1HPGD | |
| SCHEMBL9692890 | 0.77 | SMN1; SMN2 (0.41) | ACAT1LMNAHTTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |