Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025481 | 0.81 | HSP90AB1 (0.46) | ALDH1A1MAPK1L3MBTL1KMT2APOLB | |
| SCHEMBL4434815 | 0.74 | CALM1 (0.41) | ALDH1A1BRD4CALM1LMNAL3MBTL1 | |
| SCHEMBL9026500 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1LMNAHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL1563589 | 0.73 | SMN1; SMN2 (0.56) | ALDH1A1BRD4CALM1SMN1; SMN2KMT2A | |
| SCHEMBL11330543 | 0.73 | KCNH2 (0.62) | ALDH1A1BRD4CALM1RAB9ASMN1; SMN2 | |
| SCHEMBL10529725 | 0.72 | ALDH1A1 (0.48) | ALDH1A1BRD4CALM1FEN1RAB9A | |
| SCHEMBL10728920 | 0.72 | APOBEC3A (0.47) | ALDH1A1BRD4SMN1; SMN2KMT2APOLB | |
| SCHEMBL10730430 | 0.72 | NOS3 (0.46) | L3MBTL1NOS3NOS1NOS2POLB | |
| SCHEMBL19413635 | 0.71 | NOS3 (0.41) | ALDH1A1HSD17B10MAPK1NOS3NOS1 | |
| SCHEMBL19591020 | 0.71 | GRM4 (0.43) | ALDH1A1BRD4CALM1L3MBTL1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |