Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | MME | P08473 | 3/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502323 | 1.00 | LTA4H (0.57) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL7318304 | 0.87 | CTSL (0.65) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL28064932 | 0.86 | LTA4H (0.57) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL9068539 | 0.86 | MME (0.64) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL2555277 | 0.86 | LTA4H (0.57) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL6303137 | 0.86 | PSMB5 (0.67) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL9571896 | 0.84 | CTSS (0.63) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL11113189 | 0.84 | CTSS (0.63) | LTA4HMMEANPEPECE1ACE | |
| SCHEMBL30514280 | 0.84 | MMP1 (0.61) | — | |
| SCHEMBL9571894 | 0.84 | CTSS (0.63) | LTA4HMMEANPEPECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200426-A | Preventing the growth or differentiation of common acute lymphoblastic leukemia antigen and human leukemia cells | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 1993-04-06 | — | — | US | disclosed |