Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383551 | 0.84 | ITGA4 (0.50) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL9189784 | 0.84 | ATM (0.43) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL7292665 | 0.83 | ATM (0.47) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL29477122 | 0.81 | SLC7A5 (0.54) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL17154025 | 0.79 | CTSS (0.51) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL18912852 | 0.78 | CTSS (0.50) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL2581152 | 0.78 | ALDH1A1 (0.49) | SRRCYP1A2TDP1 | |
| SCHEMBL31525044 | 0.77 | CTSK (0.65) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL27756797 | 0.75 | CYP1A2 (0.49) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL9283226 | 0.74 | SLC7A5 (0.43) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546115-A1 | PEPTIDES CONTAINING AMINO-POLYOLS AS TRANSITION-STATE MIMICS | THE UPJOHN COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0344189-A1 | RENIN-INHIBITORY PEPTIDES HAVING AN EPOXIDE OR GLYCOL MOIETY | THE UPJOHN COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0218688-A1 | DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS. | UPJOHN CO (US) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986006379-A1 | DIHALO-STATINE SUBSTITUTED RENIN INHIBITORS | THE UPJOHN COMPANY (US) | 1986-11-06 | — | — | WO | disclosed |