Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505825 | 0.86 | ALDH1A1 (0.49) | POLBALDH1A1L3MBTL1KMT2AGAA | |
| SCHEMBL9506718 | 0.85 | POLB (0.49) | POLBALDH1A1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9503986 | 0.85 | KMT2A (0.56) | POLBALDH1A1L3MBTL1KMT2AGAA | |
| SCHEMBL9505856 | 0.84 | L3MBTL1 (0.63) | POLBALDH1A1L3MBTL1KMT2AGAA | |
| SCHEMBL9507663 | 0.84 | KMO (0.51) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL9503965 | 0.82 | L3MBTL1 (0.69) | ALDH1A1TDP1L3MBTL1CYP2C19KMT2A | |
| SCHEMBL10253260 | 0.81 | CYP2C9 (0.65) | POLBL3MBTL1CYP2C9CYP2C19KMT2A | |
| SCHEMBL28731474 | 0.79 | L3MBTL1 (0.64) | POLBL3MBTL1CYP2C9CYP2C19KMT2A | |
| SCHEMBL9839770 | 0.78 | ALDH1A1 (0.54) | POLBALDH1A1TDP1UTS2RL3MBTL1 | |
| SCHEMBL10252945 | 0.78 | POLB (0.68) | POLBL3MBTL1CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395991-B1 | 3-AMINOPHENYL-1,5-PENTANEDIONES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | disclosed |
| US-5053524-A | Intermediate for synthesis of triphenylcyclopentadiene dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |