Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504574 | 0.92 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL9504487 | 0.85 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| Hydrochloric Acid SCHEMBL9505511 | 0.84 | ADRA1D (0.73) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL9157336 | 0.77 | DRD2 (0.60) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9237628 | 0.77 | DRD2 (0.51) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL9504591 | 0.76 | SIGMAR1 (0.59) | SIGMAR1EBPTMEM97 | |
| Hydrochloric Acid SCHEMBL9715565 | 0.76 | DRD2 (0.58) | ADRA1DADRA1AADRA1BSIGMAR1 | |
| SCHEMBL9503531 | 0.76 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL30582757 | 0.75 | SIGMAR1 (0.73) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9506540 | 0.74 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BSIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321967-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0321967-A2 | Compounds active on the cardiovascular system | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | disclosed |