Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | EBP | Q15125 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503698 | 0.92 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL9504487 | 0.83 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| Hydrochloric Acid SCHEMBL9505511 | 0.82 | ADRA1D (0.73) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL9504591 | 0.74 | SIGMAR1 (0.59) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9503531 | 0.74 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| SCHEMBL30582757 | 0.73 | SIGMAR1 (0.73) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9506540 | 0.73 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BSIGMAR1EBP | |
| Hydrochloric Acid SCHEMBL8203328 | 0.72 | SIGMAR1 (0.74) | SIGMAR1EBPTMEM97 | |
| Hydrochloric Acid SCHEMBL30961584 | 0.72 | ALDH1A1 (0.59) | SIGMAR1EBPTMEM97 | |
| Hydrochloric Acid SCHEMBL9505408 | 0.72 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BSIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321967-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |