Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501914 | 0.88 | KMT2A (0.57) | CETPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9504171 | 0.76 | CETP (0.58) | CETPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5010196 | 0.73 | CETP (0.63) | CETPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30738545 | 0.72 | CETP (0.53) | CETPKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28926989 | 0.71 | CETP (0.57) | CETPKMT2AMEN1ALDH1A1SOAT1 | |
| SCHEMBL30102565 | 0.71 | CETP (0.54) | CETPKMT2AMEN1ALDH1A1SOAT1 | |
| SCHEMBL30107585 | 0.70 | HPGD (0.46) | CETPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9505535 | 0.70 | ACAT1 (0.69) | CETPALDH1A1MAPTLMNAHDAC3 | |
| SCHEMBL30107591 | 0.70 | KDM4E (0.48) | CETPKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL23073777 | 0.69 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |