SCHEMBL9504155

SCHEMBL9504155

FC(F)(F)C(F)(Oc1ccccc1)C(F)(F)OC(F)(F)C(F)(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LTA4H P09960 1/20 0.35
MAOB P27338 1/20 0.34
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CA4 P22748 1/20 0.32
KIF11 P52732 2/20 0.30
MLYCD O95822 1/20 0.30
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10604957 0.86 TSHR (0.41) TSHRLTA4HCA5ACA5BALDH1A1
SCHEMBL29207162 0.79 MAOB (0.30) MAOB
SCHEMBL29085967 0.78 KIF11 (0.41) LTA4HKIF11
SCHEMBL6000951 0.77 LTA4H (0.41) TSHRLTA4HCA5ACA5BALDH1A1
SCHEMBL4450519 0.72 CA5A (0.33) TSHRLTA4HCA5ACA5BMLYCD
SCHEMBL24615573 0.72 LTA4H (0.41) TSHRLTA4HCA5ACA5BALDH1A1
SCHEMBL496801 0.72 LTA4H (0.41) TSHRLTA4HCA5ACA5BALDH1A1
SCHEMBL168125 0.71 KIF11 (0.47) TSHRLTA4HKIF11
SCHEMBL6468423 0.70 LTA4H (0.39) TSHRLTA4HCA5ACA5BALDH1A1
SCHEMBL10779500 0.70 LTA4H (0.52) TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395895-B1 MELT PROCESSABLE TFE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-30 EP disclosed
EP-0225792-B1 BLENDS OF FLUOROPLASTICS AND FLUOROELASTOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP disclosed
US-5051479-A Tetrafluoroethylene copolymer with a perfluoro(alkyl vinyl ether) for extrusion E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-24 US disclosed
EP-0395895-A1 Melt processable TFE copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-07 EP disclosed
US-4713418-A CURABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-15 US disclosed
EP-0225792-A2 Blends of fluoroplastics and fluoroelastomers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-16 EP disclosed