Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 4/20 | 0.41 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109399 | 0.87 | MAOB (0.48) | KMT2AMAPK1TLR4TLR2MAOB | |
| SCHEMBL27600825 | 0.87 | CHRNB2 (0.60) | MAPTCHRNB2CHRNA4MAOBLMNA | |
| SCHEMBL28456801 | 0.86 | MAPT (0.32) | MAPTMEN1KMT2AMAPK1RECQL | |
| SCHEMBL7465350 | 0.85 | ALOX5 (0.48) | TLR4TLR2MAOBMAOA | |
| SCHEMBL3889092 | 0.84 | KCNA3 (0.46) | MAPTMEN1KMT2ARECQLTLR4 | |
| SCHEMBL9638902 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2AMAPK1RECQL | |
| SCHEMBL6438271 | 0.80 | AGXT (0.53) | MAPTMEN1KMT2AMAPK1TLR4 | |
| Anisole SCHEMBL28098758 | 0.76 | CA4 (0.52) | MAPTMEN1KMT2ATLR4TLR2 | |
| SCHEMBL27820910 | 0.74 | ALDH1A1 (0.63) | MAPTMEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL7465418 | 0.74 | HDAC1 (0.46) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |