Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504158 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL15498199 | 0.74 | CHRNB2 (0.73) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29547480 | 0.72 | CHRNB2 (0.65) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL27600825 | 0.71 | CHRNB2 (0.60) | MAPTALDH1A1CHRNB2CHRNA4LMNA | |
| SCHEMBL28109399 | 0.71 | MAOB (0.48) | ALDH1A1KMT2AMAPK1TLR4TLR2 | |
| SCHEMBL9561277 | 0.71 | CHRNB2 (0.59) | MAPTALDH1A1MEN1KMT2ACHRNB2 | |
| SCHEMBL15720996 | 0.71 | CHRNB2 (0.63) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9795834 | 0.71 | KDM4E (0.48) | MAPTALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL15219217 | 0.71 | KDM4E (0.57) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL22269212 | 0.70 | MAOA (0.48) | MAPTMEN1KMT2AMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292985-B1 | PROCESS FOR PREPARING 2,4-DINITRO-PHENYLETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4847426-A | Process for the preparation of 2,4-dinitrophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0292985-A1 | Process for preparing 2,4-dinitro-phenylethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0124084-B1 | PROCESS FOR THE PREPARATION OF 6-CHLORO-2,4-DINITROPHENOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |
| US-4540832-A | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0124084-A2 | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-07 | — | — | EP | disclosed |