Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504188 | 1.00 | MMP2 (0.54) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL607885 | 0.85 | ITGB3 (0.60) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL607886 | 0.85 | ITGB3 (0.60) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL1980652 | 0.80 | ITGB3 (0.57) | MMP2MMP9CA1CA2ERAP2 | |
| SCHEMBL8847374 | 0.80 | ITGB3 (0.57) | MMP2MMP9CA1CA2ERAP2 | |
| SCHEMBL1980150 | 0.80 | ITGB3 (0.57) | MMP2MMP9CA1CA2ERAP2 | |
| SCHEMBL6810961 | 0.80 | ITGB3 (0.55) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL22312697 | 0.80 | ITGB3 (0.55) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL7390292 | 0.80 | ITGB3 (0.55) | MMP2MMP9CA1CA2FOLH1 | |
| SCHEMBL9388898 | 0.80 | C3AR1 (0.47) | FOLH1ITGB3ITGA2BKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300849-B1 | PROCESS FOR THE CHEMICAL MODIFICATION OF PROTIDES, AND PRODUCTS SO MODIFIED | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-06-16 | — | — | EP | disclosed |
| US-4870016-A | CHANGING SOLUBILITY OF ENZYMES | LEVESQUE GUY (FR) | 1989-09-26 | — | — | US | disclosed |
| EP-0300849-A1 | Process for the chemical modification of protides, and products so modified | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1989-01-25 | — | — | EP | disclosed |