Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.51 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.51 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.51 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980150 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BC3AR1CA2PDE4A | |
| SCHEMBL8847374 | 1.00 | ITGB3 (0.57) | ITGB3ITGA2BC3AR1CA2PDE4A | |
| SCHEMBL607886 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BC3AR1CA2PDE4A | |
| SCHEMBL607885 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BC3AR1CA2PDE4A | |
| SCHEMBL29775626 | 0.90 | ITGB3 (0.53) | ITGB3ITGA2BC3AR1CA2GRIN1 | |
| SCHEMBL7390292 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BC3AR1CA2ERAP2 | |
| SCHEMBL6810961 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BC3AR1CA2ERAP2 | |
| SCHEMBL22312697 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BC3AR1CA2ERAP2 | |
| SCHEMBL4987446 | 0.89 | C3AR1 (0.72) | ITGB3ITGA2BC3AR1CA2ERAP2 | |
| SCHEMBL27772282 | 0.89 | C3AR1 (0.72) | ITGB3ITGA2BC3AR1CA2ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3040417-B1 | MACROCYCLIC PEPTIDE, METHOD FOR PRODUCING SAME, AND SCREENING METHOD USING MACROCYCLIC PEPTIDE LIBRARY | UNIV TOKYO (JP) | 2023-12-13 | — | — | EP | disclosed |
| US-10234460-B2 | Macrocyclic peptide, method for producing same, and screening method using macrocyclic peptide library | THE UNIVERSITY OF TOKYO (JP) | 2019-03-19 | — | — | US | disclosed |
| US-20160209421-A1 | Macrocyclic Peptide, Method for Producing Same, and Screening Method Using Macrocyclic Peptide Library | THE UNIVERSITY OF TOKYO (JP) | 2016-07-21 | — | — | US | disclosed |
| EP-3040417-A1 | MACROCYCLIC PEPTIDE, METHOD FOR PRODUCING SAME, AND SCREENING METHOD USING MACROCYCLIC PEPTIDE LIBRARY | The University of Tokyo (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-7964636-B2 | Synthesis and use of novel inhibitors and inactivators of protein arginine deiminases | UNIVERSITY OF SOUTH CAROLINA (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090306153-A1 | SYNTHESIS AND USE OF NOVEL INHIBITORS AND INACTIVATORS OF PROTEIN ARGININE DEIMINASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2007056389-A2 | SYNTHESIS AND USE OF NOVEL INHIBITORS AND INACTIVATORS OF PROTEIN ARGININE DEIMINASES | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-05-18 | — | — | WO | disclosed |
| CN-1109780-A | Sustained-release preparation of anti-endothelin substance | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4325961-A | FLUOROMETHYLHISTIDINE, ESTERS, AND SALTS | MERCK & CO., INC. (US) | 1982-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10234460-B2 | Macrocyclic peptide, method for producing same, and screening method using macrocyclic peptide library | VIP, SLC7A1, PITRM1 | ITGB3 4722/4885ITGA2B 4662/4885C3AR1 964/4885 |
| US-20160209421-A1 | Macrocyclic Peptide, Method for Producing Same, and Screening Method Using Macrocyclic Peptide Library | VIP, SLC7A1, PITRM1 | ITGB3 4722/4885ITGA2B 4662/4885C3AR1 964/4885 |
| US-20090306153-A1 | SYNTHESIS AND USE OF NOVEL INHIBITORS AND INACTIVATORS OF PROTEIN ARGININE DEIMINASES | PADI1, PADI4, PADI2 | ITGB3 4736/4885ITGA2B 4749/4885C3AR1 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.