SCHEMBL9504373

SCHEMBL9504373

O=C(O)CC(Cl)C(F)(F)Cl

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
GABRR1 P24046 2/20 0.32
LMNA P02545 2/20 0.32
TSHR P16473 3/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866600 0.79 SLC22A6 (0.41) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL7592946 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL1132009 0.72 SLC22A6 (0.39) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL8466906 0.70 ALDH1A1 (0.30) SLC22A6ALDH1A1
SCHEMBL11299621 0.70 SLC22A6 (0.33) SLC22A6TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL11295122 0.69 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
SCHEMBL11295903 0.69 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
SCHEMBL820375 0.68 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
Trifluoroethanol SCHEMBL6715198 0.68 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL10525649 0.67 ALDH1A1 (0.31) SLC22A6TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357742-B1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES ROUSSEL-UCLAF (FR) 1993-06-09 EP disclosed
EP-0357742-A1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES. ROUSSEL UCLAF (FR) 1990-03-14 EP disclosed
WO-1989008096-A1 NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES ROUSSEL-UCLAF (FR) 1989-09-08 WO disclosed