SCHEMBL9504489

SCHEMBL9504489

CC(C)(C)c1ccccc1[SiH2][SiH3]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
CA2 P00918 1/20 0.41
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
KIF11 P52732 1/20 0.34
PLA2G1B P04054 1/20 0.31
MAPT P10636 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506576 0.82 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL15655352 0.76 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL2272712 0.76 TDP1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL27173776 0.76 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL2273300 0.74 ALDH1A1 (0.43) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL19921960 0.74 ALDH1A1 (0.43) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL2272999 0.73 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL17077609 0.73 TDP1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL1576167 0.73 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL29355273 0.73 ALDH1A1 (0.63) ALDH1A1TDP1TSHRCA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed