SCHEMBL2272999

SCHEMBL2272999

CN[SiH2]c1ccccc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA2 P00918 1/20 0.38
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
KIF11 P52732 1/20 0.32
MAPT P10636 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
POLB P06746 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268949 0.78 TSHR (0.38) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL27173776 0.77 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL1576167 0.74 ALDH1A1 (0.41) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL15655352 0.73 ALDH1A1 (0.50) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL9504489 0.73 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL2272712 0.73 TDP1 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL2103819 0.72 ALDH1A1 (0.33) ALDH1A1TSHRTDP1CA2GAA
SCHEMBL2103512 0.71 CACNA2D1 (0.33) ALDH1A1TSHRTDP1GAAKDM4E
SCHEMBL19921960 0.71 ALDH1A1 (0.43) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL2273300 0.71 ALDH1A1 (0.43) ALDH1A1TSHRTDP1CA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed