Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | CD14 | P08571 | 1/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504435 | 0.98 | LTB4R (0.37) | PDE3BPDE3AP2RY12LMNAPOLB | |
| SCHEMBL9417715 | 0.79 | CA2 (0.47) | LMNAPOLBGAA | |
| SCHEMBL9417725 | 0.78 | CA2 (0.46) | LMNAPOLBLTB4RGAAPLA2G2A | |
| SCHEMBL9417678 | 0.78 | CA2 (0.46) | LMNAPOLBLTB4RGAAPLA2G2A | |
| SCHEMBL6130948 | 0.75 | PDE3B (0.42) | PDE3BPDE3AP2RY12L3MBTL1LTB4R | |
| SCHEMBL11415045 | 0.75 | CASP1 (0.35) | — | |
| SCHEMBL7879116 | 0.74 | GABRA1 (0.41) | LMNAPOLBHTTL3MBTL1CNR1 | |
| SCHEMBL9417684 | 0.73 | CA2 (0.49) | LMNAPOLBGAA | |
| SCHEMBL1722335 | 0.72 | TLR4 (0.55) | TLR4CD14LY96 | |
| SCHEMBL2678696 | 0.72 | GABRA1 (0.38) | LMNAPOLBHTTL3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288305-B1 | DI-T-BUTYLPHENYL ALKYL AND BENZYL ETHERS | RIKER LABORATORIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4973731-A | Di-t-butylphenyl alkyl and benzyl ether nitriles | RIKER LABORATORIES, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0288305-A1 | Di-t-butylphenyl alkyl and benzyl ethers | RIKER LABORATORIES, INC. (US) | 1988-10-26 | — | — | EP | disclosed |