Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357158 | 0.77 | CYSLTR2 (0.48) | FAAHCES1MGLLCYP4F2CYP4A11 | |
| SCHEMBL9357156 | 0.77 | CYSLTR2 (0.48) | FAAHCES1MGLLCYP4F2CYP4A11 | |
| SCHEMBL9501796 | 0.73 | PLA2G4B (0.41) | PLA2G4BPLA2G4APLA2G2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9504626 | 0.72 | NPC1 (0.43) | FAAHPLA2G4BPLA2G4APLA2G2AALDH1A1 | |
| SCHEMBL9503595 | 0.71 | CYSLTR2 (0.57) | FAAHCES1MGLLCYP4F2CYP4A11 | |
| SCHEMBL9502590 | 0.71 | CYSLTR2 (0.47) | FAAHPLA2G4BPLA2G4APLA2G2A | |
| SCHEMBL9501760 | 0.70 | CYSLTR2 (0.48) | FAAHCES1 | |
| SCHEMBL9356626 | 0.69 | CYSLTR2 (0.48) | FAAHCES1MGLLCYP4F2CYP4A11 | |
| SCHEMBL9369239 | 0.69 | CYSLTR2 (0.48) | FAAHCES1MGLLCYP4F2CYP4A11 | |
| SCHEMBL9429346 | 0.69 | CYSLTR2 (0.43) | FAAHCES1MGLLCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |