Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504626 | 0.79 | NPC1 (0.43) | PLA2G4BPLA2G4APLA2G2AALDH1A1MEN1 | |
| SCHEMBL9504619 | 0.73 | FAAH (0.41) | PLA2G4BPLA2G4APLA2G2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9501572 | 0.70 | TP53 (0.45) | PLA2G4BPLA2G4APTGS2 | |
| SCHEMBL9501466 | 0.67 | ALDH1A1 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8937745 | 0.67 | CYSLTR2 (0.47) | PLA2G4BPLA2G4APLA2G2A | |
| SCHEMBL9364503 | 0.67 | CYSLTR2 (0.47) | PLA2G4BPLA2G4APLA2G2A | |
| SCHEMBL14093841 | 0.66 | PLA2G4B (0.47) | PLA2G4BPLA2G4APLA2G2APLK1HTT | |
| SCHEMBL9428739 | 0.66 | PTGER1 (0.46) | PLA2G4BPLA2G4APLA2G2AHTT | |
| SCHEMBL9502590 | 0.64 | CYSLTR2 (0.47) | PLA2G4BPLA2G4APLA2G2APOLB | |
| SCHEMBL14093897 | 0.64 | PLA2G4B (0.46) | PLA2G4BPLA2G4APLA2G2APLK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |