Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501796 | 0.79 | PLA2G4B (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9503373 | 0.75 | CYSLTR2 (0.47) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL9505492 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL9504619 | 0.72 | FAAH (0.41) | SMN1; SMN2KDM5BALDH1A1FAAHPLA2G4B | |
| SCHEMBL9503345 | 0.70 | CYSLTR2 (0.47) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL9501780 | 0.69 | PLA2G7 (0.44) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL9502622 | 0.69 | LTB4R (0.40) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL14384336 | 0.68 | SIGMAR1 (0.54) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL9501799 | 0.67 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2KDM6BKDM4A | |
| SCHEMBL14384322 | 0.67 | SIGMAR1 (0.51) | NPC1KDM6BKDM4AKDM4DKDM3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | claimed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | claimed |