Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562610 | 0.81 | NUDT1 (0.43) | GAALMNAPKMMAPTHTT | |
| SCHEMBL2177550 | 0.80 | GAA (0.60) | GAALMNAPKMMAPTHTT | |
| SCHEMBL29822675 | 0.80 | GAA (0.60) | GAALMNAPKMMAPTHTT | |
| SCHEMBL6887750 | 0.77 | GAA (0.73) | GAALMNAPKMMAPTHTT | |
| SCHEMBL9671638 | 0.77 | HSD17B10 (0.66) | GAALMNAPKMHSD17B10POLB | |
| SCHEMBL230024 | 0.76 | GAA (0.78) | GAALMNAPKMMAPTHTT | |
| SCHEMBL7080316 | 0.74 | GAA (0.53) | GAALMNAPKMMAPTHTT | |
| SCHEMBL28644823 | 0.74 | RAB9A (0.68) | GAALMNAPKMMAPTHTT | |
| SCHEMBL2177536 | 0.74 | LMNA (0.64) | GAALMNAPKMMAPTHTT | |
| SCHEMBL29725701 | 0.74 | RAB9A (0.68) | GAALMNAPKMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180723-A | Hypertensives, bronchodilators, antiedemic agents | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-01-19 | — | — | US | disclosed |